Timd4 CLIA Kit for Mouse(Mus musculus) | EIAab.comTimd4 CLIA Kit for Mouse(Mus musculus)

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Timd4 (Gene name),

T-cell immunoglobulin and mucin domain-containing protein 4 (Protein name ), TIMD4_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Timd4(Tim4);

Protein name:

T-cell immunoglobulin and mucin domain-containing protein 4(TIMD-4);

Alternative:

T-cell membrane protein 4(TIM-4);Spleen, mucin-containing, knockout of lymphotoxin protein(SMUCKLER);TIM-4;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer.

Function:

Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Involved in regulating T-cell proliferation and lymphotoxin signaling. Ligand for HAVCR1/TIMD1.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

343

Sequence:

50:

100:

150:

200:

250:

300:

343:

LRGKVTGANC | LQRHKRPDNT | EDSDSVLNDM | SHGRDDEDGI | FTL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07686

String:

Q6U7R4

STRING:

10090.ENSMUSP00000069456

UniGene:

Mm.69002

SMR:

Q6U7R4

KEGG:

mmu:276891

Uniprot:

Q6U7R4

FOR

ELISA Kit for Mouse TIMD-4

Cat.:

E13605m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Mouse TIMD-4

Cat.:

E13605h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TIMD-4

Cat.:

U13605m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TIMD-4

Cat.:

U13605h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse TIMD-4

Cat.:

P13605Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse TIMD-4

Cat.:

P13605Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse TIMD-4

Protein for Mouse TIMD-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling."
Shakhov A.N. , Rybtsov S. , Tumanov A.V. , Shulenin S. , Dean M. , Kuprash D.V. , Nedospasov S.A.
Eur. J. Immunol.34:494-503(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS MET-12 AND 209-ILE;FUNCTION;INDUCTION;TISSUE SPECIFICITY
strain: BALB/c.
strain: C57BL/6.
2.

"TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation."
Meyers J.H. , Chakravarti S. , Schlesinger D. , Illes Z. , Waldner H. , Umetsu S.E. , Kenny J. , Zheng X.X. , Umetsu D.T. , DeKruyff R.H. , Strom T.B. , Kuchroo V.K.
Nat. Immunol.6:455-464(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HAVCR1/TIM1
3.

"Identification of Tim4 as a phosphatidylserine receptor."
Miyanishi M. , Tada K. , Koike M. , Uchiyama Y. , Kitamura T. , Nagata S.
Nature450:435-439(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBUNIT
4.

"Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine binds."
Santiago C. , Ballesteros A. , Martinez-Munoz L. , Mellado M. , Kaplan G.G. , Freeman G.J. , Casasnovas J.M.
Immunity27:941-951(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS) OF 25-134 IN COMPLEX WITH PHOSPHATIDYLSERINE;DISULFIDE BONDS

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